Phenotypic switching of antibiotic resistance circumvents permanent costs in Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Phenotypic switching of antibiotic resistance circumvents permanent costs in Staphylococcus aureus
Bacterial antibiotic resistance is often associated with a fitness cost in the absence of the antibiotic [1,2]. We have examined a resistance mechanism in Staphylococcus aureus that negates these costs. Exposure to gentamicin both in vitro and in vivo has been reported to result in the emergence of a gentamicin-resistant small colony variant (SCV)[3-8]. We show that the emergence of SCVs follow...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2001
ISSN: 0960-9822
DOI: 10.1016/s0960-9822(01)00507-3